New vaccines and antiviral drugs for cytomegalovirus
نویسندگان
چکیده
منابع مشابه
Antiviral drugs for cytomegalovirus diseases.
Cytomegalovirus infections are associated with severe morbidity and mortality is patients at risk for disease because of immune system disabilities; in particular, recipients of stem cell (HSCT) or solid organ (SOT) transplants. There are three systemic drugs approved for CMV treatment: ganciclovir, or its prodrug valganciclovir, foscarnet, and cidofovir. An anti-sense therapeutic, ISIS 2922, i...
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While measures such as closing schools and social distancing may slow the effects of pandemic influenza, only vaccines and antiviral drugs are clearly efficacious in preventing infection or treating illness. Unless the pandemic strain closely resembles one already recognized, vaccine will not be available early. However, studies can be conducted beforehand to address questions concerning vaccin...
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Human cytomegalovirus (HCMV) infections are common and lead to lifelong infections. In immunocompetent individuals, primary infections are mostly subclinical or they may be associated with a self-limited mononucleosis-like syndrome. In contrast, infections in immunocompromised hosts (either primary infections, reactivations from latency, or reinfections) are associated with important morbidity ...
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Resistance of cytomegalovirus (CMV) to antiviral agents is a well-recognized phenomenon that has been observed in the laboratory and in the clinical setting. Infections caused by antiviral-resistant CMV have been found exclusively among immunocompromised individuals, including patients with AIDS, bone marrow and solid-organ transplant recipients, and patients with hematologic malignancies, and ...
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We thank all the respondents to the survey and the nurses at the Leicestershire Hospice for their interest and willing participation, Dr Carol Jagger for statistical help, and Miss K Jeffery for preparing the typescript. I St Christopher"s Hospice Iniformation Service. 1988 Direcion, of liospiCe serz.ices. Svdcnliaini: St (hristopher's Hospice, 1988. 2 Hill F, Oliver C. Hospice-thc cost of in-p...
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ژورنال
عنوان ژورنال: Journal of Clinical Virology
سال: 2019
ISSN: 1386-6532
DOI: 10.1016/j.jcv.2019.04.007